$76,000 – $100,0009h ago
Molecule and BIO.xyz are building the foundation of Decentralized Science (DeSci) — where biotech meets web3 to make scientific research community-owned, transparent, and faster to market.
Molecule provides the infrastructure to turn intellectual property (IP) into programmable, on-chain assets through our IP-NFT framework and evolving protocol stack. This enables researchers, patients, and communities to fund and govern biotech projects in new, open ways.
BIO.xyz is the coordination and economic layer of DeSci, powering BioDAOs through funding, governance, and ecosystem alignment.
Together, we are creating a new model for scientific discovery — one where breakthroughs are owned and advanced by the communities that believe in them.
Location: Germany (lab site TBC - right candidate informs final location)
Type: Senior IC role - no team to manage on day one; you hire your team in year two once the proof exists
Capsules. Tablets. Sterile compounding. We're building precisely-dosed formulations of cognitive, performance, and longevity compounds - modafinil, bromantane, GLP-1 analogs, BPC-157, thymosin α-1, and a growing pipeline of small-molecule and peptide actives.
You will set our formulation standards, run the bench work, and be the person who can defend every excipient choice, every dissolution curve, and every sterility result. From active properties to qualified drug product - oral, injectable, topical - with documentation that holds up.
Design oral solid-dose formulations (capsules and tablets) from active properties up - excipient selection, diluents, binders, disintegrants, flow agents, and lubricants matched to each compound's solubility, stability, and dosing profile
Design sterile injectable formulations for our peptide pipeline - lyophile design, bulking agents, cryoprotectants, vial fill/finish at small scale, reconstitution protocols, and container-closure compatibility. Hands-on with EU GMP Annex 1 (sterile manufacturing) and applicable AMG/AMWHV requirements
Own encapsulation, blending, and aseptic processing end to end: powder characterization, blend uniformity, content uniformity, capsule fill weight control, scale-up from bench to production batches, and sterility assurance for the injectable side
Solve hard actives. Bromantane and modafinil bring oral-side challenges - low aqueous solubility, poor flow, dose accuracy at small fill weights. Peptides like BPC-157, GLP-1 analogs, and GHK-Cu bring injectable-side challenges - stability across the lyophile/reconstitution cycle, copper-complex integrity, peptide aggregation. You develop the techniques that make all of them reproducible
Build and run the analytical backbone: dissolution testing, assay/potency, content and weight uniformity, sterility (Ph. Eur. 2.6.1), endotoxin (Ph. Eur. 2.6.14), and stability programs (ICH Q1A - accelerated and long-term) to establish shelf life
Write documentation that holds up: master formulation records, batch records, specifications, and SOPs. Define what "in spec" means and enforce it. Clean data trails or it didn't happen
Partner with sourcing and QC on raw-material specs, incoming API characterization (identity, purity by HPLC, particle size), and supplier qualification. Build a qualified supplier network. Continuously improve - reduce variability, improve stability, lower cost-per-dose without compromising quality
Defends decisions with data. You'd rather run the test than guess. When asked why you chose X over Y, you have a data-grounded answer
High bar on accuracy and sterility. It's people's health. Dose accuracy, reproducibility, and sterility are non-negotiable - especially on injectables
Expert in the room alone. You work well as the sole expert on day one. No team around you for the first year, and that doesn't slow you down
Engineers around complexity. You see the regulatory complexity of the compound classes we work with clearly, and you engineer around it rather than pretending it isn't there
Approbation als Apotheker/in (German pharmacist license), or an EU-recognized pharmacy qualification with a clear path to German licensure. Alternatively: a degree in pharmaceutics, pharmaceutical sciences, or industrial pharmacy (MSc/PhD) with equivalent hands-on formulation depth
5+ years of hands-on formulation experience in pharma, nutraceutical, compounding, or contract manufacturing - covering oral solid dose and at least one of: sterile injectables, topicals
Deep working knowledge of excipient functionality and compatibility, and of encapsulation/tableting unit operations
Practical command of dissolution, content uniformity, and stability study design and interpretation
Experience formulating poorly-soluble or low-dose actives
Working command of EU GMP (EudraLex Vol. 4), Annex 1 (sterile manufacturing), and the Apothekenbetriebsordnung (ApBetrO) or equivalent manufacturing-pharmacy framework
Rigor with documentation: batch records, specs, SOPs, and a clean data trail
Sterile injectable / lyophilization experience - peptide formulations specifically
Background in a German Herstellungsapotheke, hospital pharmacy compounding unit, or EU-licensed contract manufacturer
Experience formulating GLP-1 analogs (semaglutide, tirzepatide) or other peptide manufacturing under a quality-grade framework
Familiarity with cognitive/performance compounds, or with the broader peptide / longevity therapeutic landscape
Hands-on with HPLC, dissolution apparatus, particle sizing, Karl Fischer titration
Comfort owning scale-up from R&D batches to production
Working proficiency in German (regulatory and documentation context) and English (team working language)
A senior IC seat building the formulation function from scratch at a company at the intersection of biotech, blockchain, and AI
Pre-approved capex - you spec the equipment: lyophilizer, capsule filler, balance suite, HPLC, dissolution apparatus, Class II BSC
The team you need, once you've proven the foundation
Submit your CV and a Cover Letter describing which formulation problem from our pipeline would you most want to solve? Two paragraphs max on each of (a) which problem, (b) why, and (c) what you'd need to do it well.
We are an equal opportunity employer. We are committed to equality and weaving a community that values diverse perspectives and experiences and are actively seeking a diverse pool of applicants. All employment decisions are made without regard to race, colour, national origin, ancestry, sex, gender, gender identity or expression, sexual orientation, age, genetic information, religion, disability, medical condition, pregnancy, marital status, family status, veteran status, or any other characteristic protected by law.
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